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目的:探讨中医温阳健脾法联合西药治疗2型糖尿病胰岛素抵抗的临床疗效。方法:选取2012年1月至2014年12月期间在本院接受治疗的2型糖尿病胰岛素抵抗患者100例,采用随机数字法将患者分为观察组与对照组,每组各50例。对照组患者以西药二甲双胍与格列吡嗪进行治疗,观察组患者在此基础上联合中医温阳健脾法同时治疗,对两组患者的治疗效果进行观察比较。结果:治疗总有效率比较:观察组患者治疗总有效率为90%(45/50)、对照组患者治疗总有效率为68%(34/50),组间比较,差异具有统计学意义(P<0.05);血糖值改善比较:治疗后观察组患者在空腹血糖(FPG)、餐后2h血糖(2 h PG)与糖化血红蛋白(Hb A1c)等指标上改善优于对照组,组间比较,差异具有统计学意义(P<0.05);空腹胰岛素(FINS):治疗后观察组患者的FINS显著低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:中医温阳健脾法联合西药治疗2型糖尿病胰岛素抵抗者临床效果显著。
Objective: To investigate the clinical effect of warming yang invigorating the spleen method combined with Western medicine in treating type 2 diabetes with insulin resistance. Methods: A total of 100 patients with type 2 diabetes mellitus with insulin resistance treated in our hospital from January 2012 to December 2014 were enrolled. Patients were divided into observation group and control group by random number method, with 50 cases in each group. The patients in the control group were treated with metformin and glipizide. The patients in the observation group were treated with the method of warming yang and invigorating the spleen simultaneously, and the therapeutic effect of the two groups was observed and compared. Results: The total effective rate of treatment: The total effective rate was 90% (45/50) in the observation group and 68% (34/50) in the control group. The differences between the two groups were statistically significant ( (P <0.05). Compared with the control group, the improvement of blood glucose in the observation group was better than that of the control group in fasting blood glucose (FPG), postprandial 2h blood glucose (2h PG) and Hb A1c (P <0.05). Fasting insulin (FINS): The FINS in the observation group was significantly lower than that in the control group after treatment, the difference was statistically significant (P <0.05). Conclusion: The clinical effect of warming yang and invigorating the spleen method combined with western medicine on type 2 diabetic insulin resistance is remarkable.