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目的探讨同步放化疗治疗中晚期宫颈癌的疗效及毒副反应。方法2002-06-2004-12对温州市第二人民医院同步放化疗组42例中晚期宫颈癌病人用盖诺联合顺铂化疗,同时行根治性放疗;单纯放疗组44例行根治性放疗。结果同步放化疗组近期有效率92.9%,单纯放疗组77.3%。两组比较差异有显著性意义(P<0.05),毒副反应相近。结论同步放化疗治疗中晚期宫颈癌可提高近期疗效,不影响放疗进程,毒副反应无明显增加。
Objective To investigate the curative effect and toxicity of concurrent chemoradiotherapy for advanced cervical cancer. Methods From June 2002 to December 2004, 42 patients with advanced cervical cancer in the Second People’s Hospital of Wenzhou City underwent concurrent chemoradiotherapy with Gynostemol plus cisplatin while undergoing radiotherapy alone. Forty-four patients in the radiotherapy group received radical radiotherapy. The results of concurrent radiotherapy and chemotherapy group, the effective rate of 92.9%, 77.3% of radiotherapy alone group. The difference between the two groups was significant (P <0.05), similar side effects. Conclusions Simultaneous chemoradiotherapy in the treatment of advanced cervical cancer can improve the short-term curative effect, does not affect the radiotherapy process, and has no obvious increase in toxic and side effects.