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目的:提高对急性肿瘤溶解综合征(ATLS)的认识和探讨持续肾脏替代治疗(CRRT)在其急救中的作用。方法:对1例侵袭性NK/T细胞淋巴瘤化疗后并发ATLS患者,采用CRRT救治。结果:通过CRRT,患者心力衰竭症状很快得到缓解,尿量增多,高钾、代谢性酸中毒及时得到纠正,肾功能也很快得到改善,疗效显著。结论:对于ATLS患者,如果药物疗效欠佳,应及早考虑CRRT;如果患者血流动力学不稳定,不能耐受普通血液透析治疗,CRRT应成为优先考虑的治疗选择。
OBJECTIVE: To raise awareness of acute tumor lysis syndrome (ATLS) and to explore the role of continuous renal replacement therapy (CRRT) in first aid. Methods: One case of aggressive NK / T-cell lymphoma complicated with ATLS after chemotherapy was treated with CRRT. Results: Through CRRT, symptoms of heart failure were relieved quickly, urine output increased, potassium and metabolic acidosis were corrected in time, renal function was also improved rapidly, and the curative effect was remarkable. CONCLUSIONS: CRTI should be considered as early as possible if the drug is ineffective in patients with ATLS. CRRT should be considered as a treatment option if the patient is hemodynamically unstable and can not tolerate conventional hemodialysis.