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123I以其优越的核性质,如半衰期为13.2h、发射的主光子能量为159 keV、无β-发射等,特别适合于γ相机及SPECT(单光子发射断层显像)测量。123I及其标记化合物被广泛用于心脏学、神经学和肿瘤学研究和临床诊断,特别是123I标记的单克隆抗体、各种受体配体以及生物分子类似物已被广泛用于核医学临床和研究,使原来只能在PET(正电子发射断层显像)上进行的研究工作扩大到较为经济的SPECT上。
123I has excellent nuclear properties such as 13.2h half-life, 159 keV primary photon energy emission and no β-emission, which is especially suitable for gamma camera and SPECT (Single Photon Emission Tomography) measurement. 123I and its labeled compounds are widely used in cardiology, neurology and oncology research and clinical diagnosis. In particular, 123I-labeled monoclonal antibodies, various receptor ligands and biomolecular analogs have been widely used in nuclear medicine clinical And research to expand the work that could have been done on PET (positron emission tomography) to the more economical SPECT.