尿毒症皮肤瘙痒症是慢性肾脏病的常见症状之一，也是尿毒症透析患者死亡的高危因素之一，严重影响着患者的生活质量。近年来，血液透析联合血液灌流在治疗尿毒症皮肤瘙痒症方面疗效显著，本文综述了尿毒症皮肤瘙痒症的影响因子、发病机制及治疗方法，以期为该病的临床治疗提供借鉴。“,”Uremic pruritus is one of common symptoms of chronic renal disease and also one of high risk factors of death in uremia patients undergoing hemodial‐ysis ,influences patients’ quality of life seriously .In recent years hemodialysis plus hemoperfusion have an evident effect on uremic pruritus .In this paper influencing factors ,pathogenesis and therapeutic methods of uremic pruritus were analyzed in order to provide reference for clinical treatment .