肝脏是微量元素代谢的重要器官。肝功能的紊乱,会导致微量元素的代谢异常。关于急性肝衰竭肝脏和脑组织微量元素代谢的研究国内外报道很少。尤其是关于微量元素及其结合蛋白的代谢,国内未见报导。如果单研究微量元素而不研究其结合蛋白质的代谢,这种研究是不全面的。为此,我们观察了大鼠实验性急性肝衰竭时,血清、肝脏、脑组织铁、铜、锌及血清中相应结合蛋白质的变化。 The liver is an important organ for the metabolism of trace elements. Liver disorders, can lead to metabolic abnormalities of trace elements. There are few reports on the metabolism of trace elements in liver and brain tissue in acute liver failure. Especially on the metabolism of trace elements and their binding proteins, there is no report in China. This study is incomplete if you are studying trace elements alone and not studying the metabolism of their bound proteins. To this end, we observed the changes of the corresponding binding proteins in serum, liver, brain tissue of iron, copper, zinc and serum in experimental acute liver failure.