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应用自制的西安地区气传优势真菌(表霉菌、酵母菌、间链菌、烟曲菌)抗原给76例支气管哮喘患者及50例无过敏性疾病史的健康人做嗜碱粒细胞脱颗粒试验(HBDT)及过敏原皮试,比较两种试验结果,发现哮喘组的4种真菌抗原皮试及HBDT阳性率均在50％以上,显著高于对照组。皮试及HBDT的诊断符合率均在85％以上。提示作为真菌过敏性哮喘的诊断方法,HBDT特异性强,结果准确可靠,不具有体内诊断方法的副作用。
In this study, 76 cases of bronchial asthma and 50 healthy people without history of allergic diseases were used to make basophil degranulation test using self-made airborne dominant fungi (phenomycetes, yeasts, mesococci and aspergillus fumigatus) in Xi’an. (HBDT) and allergen skin test. Compared with the two test results, it was found that the positive rates of skin fungal tests and HBDT of four kinds of fungal antigens in asthma group were all above 50%, significantly higher than that of the control group. Skin test and HBDT diagnosis in line with the rate of more than 85%. As a diagnostic method for fungal allergic asthma, HBDT has strong specificity and accurate and reliable results. It does not have the side effects of in vivo diagnostic methods.