论文部分内容阅读
建立了同时分离测定化妆品中6种对羟基苯甲酸酯类防腐剂的毛细管胶束电动色谱方法。以未涂层熔融石英毛细管柱(47.5 cm×50μm i.d.,leff=39.5 cm)为分离柱,15 mmol/L Tris-H3PO4(pH 7.0)+10 mmol/L丁二酸二异辛酯磺酸钠(AOT)+体积分数10%乙腈为电泳运行液,10 cm高度差进样,10 s,20kV恒压分离,255 nm波长检测。在质量浓度1.0~200 mg/L范围内,6种组分峰面积与相应质量浓度间均具有良好的线性关系(r≥0.9995)。当信噪比(S/N)为2时,各组分的检出限为1.1~1.7 mg/kg。样品加标回收率为84.2%~122.3%。
A capillary micellar electrokinetic chromatography method was developed for simultaneous determination of 6 para-hydroxybenzoate preservatives in cosmetics. Uncoated fused silica capillary column (47.5 cm × 50 μm id, leff = 39.5 cm) was used as the separation column, and 15 mmol / L Tris-H3PO4 (pH 7.0) +10 mmol / L sodium diisooctyl sulfosuccinate (AOT) + volume fraction of 10% acetonitrile for the electrophoresis running solution, 10 cm height difference injection, 10 s, 20kV constant pressure separation, 255 nm wavelength detection. In the concentration range of 1.0 ~ 200 mg / L, there was a good linear relationship between the peak area of the six components and the corresponding mass concentration (r ≥ 0.995). When the signal to noise ratio (S / N) is 2, the detection limit of each component is 1.1-1.7 mg / kg. The recoveries of spiked samples ranged from 84.2% to 122.3%.