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目的:将丙泊酚复合瑞芬太尼和丙泊酚氯胺酮应用于小儿非插管全麻的短小手术,观察和分析比较临床效果及安全性。方法:选择愿意参与研究的35例需短小手术的患儿,将他们分成2组,A组和B组。A组在手术时采用丙泊酚复合瑞芬太尼来进行麻醉而B组采用丙泊酚氯胺酮,在手术过程中记录下患儿的SpO2、心率、呼吸频率及平均动脉压的变化,在手术结束后记录患儿的清醒时间、恢复时间及恶心呕吐的发生率。结果:手术过程中A组患儿的心率和平均动脉压有明显下降,而手术结束后的恶心呕吐发生率为4.5%;而B组在手术过程中的各项指标变化不大,手术结束后的恶心呕吐发生率为1.7%。A组的术中和术后数据与B组进行统计学比较均为P<0.05,有显著差异。结论:丙泊酚氯胺酮作为麻醉剂在短小型小儿非插管全麻手术中拥有更好的安全性,应用效果明显优于丙泊酚复合瑞芬太尼。
OBJECTIVE: To apply propofol combined with remifentanil and propofol ketamine in the short operation of non-intubated general anesthesia in children. The clinical effects and safety were observed and analyzed. METHODS: Thirty-five children who needed to participate in the study were selected and were divided into two groups, Group A and Group B. Group A was anesthetized with propofol and remifentanil during surgery, and propofol ketamine was used in group B. Changes in SpO2, heart rate, respiratory rate, and mean arterial pressure were recorded during surgery. During operation, After the record of children with awake time, recovery time and the incidence of nausea and vomiting. Results: The heart rate and mean arterial pressure of group A decreased significantly during operation, but the incidence of nausea and vomiting was 4.5% after operation. In group B, the indexes of operation were not changed much. After operation, The incidence of nausea and vomiting was 1.7%. A group of intraoperative and postoperative data and the B group statistical comparison were P <0.05, there were significant differences. CONCLUSION: Propofol ketamine has better safety in anesthesia with short pediatric non-intubation anesthesia and its effect is better than that of propofol combined with remifentanil.