药物洗脱支架可显著改善非ST段抬高急性冠脉综合征患者的心血管终点。一方面,药物支架通过抑制平滑肌细胞的增生使再狭窄率大大降低;另一方面,它又可抑制内皮细胞的增殖而导致内皮化延迟,从而有可能增加支架内血栓,尤其是晚期支架内血栓的发生风险。冠状动脉介入术后强化抗血小板策略作为预防这一危及生命的临床事件的重要手段之一,在药物洗脱支架时代已受到广泛的关注。 Drug-eluting stents can significantly improve cardiovascular outcomes in patients with non-ST-elevation acute coronary syndrome. On the one hand, the drug scaffold greatly reduces the rate of restenosis by inhibiting the proliferation of smooth muscle cells; on the other hand, it can inhibit the proliferation of endothelial cells and lead to the delay of endothelialization, which may increase intra-stent thrombosis, especially late stent thrombosis The risk of occurrence. As an important means of preventing this life-threatening clinical event, the strategy of enhancing anti-platelet after coronary intervention has drawn wide attention in the era of drug-eluting stents.