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高催乳素血症是下丘脑一垂体单位常见的疾病。近年来,由于诊断和冶疗方法的进展,使很多患者恢复正常月经并受孕。本文报告1981年5月～1985年10月间高催乳素血症80例,其中垂体肿瘤28例,功能性高催乳素血症48例,药物性原因4例。本组病例经用溴隐亭、三合激素、克罗米酚、hMG+hCG、手术或放射治疗后,月经恢复74例(92％),妊娠44例,妊娠率66.1％,其中流产8例,有一例因溢乳-闭经综合征。经手术切除垂体肿瘤和放射治疗,产生垂体功能低下性性腺功能不良性闭经。经用hMG+hcG治疗后获双胎妊娠。因此针对病因洽疗可提高疗效。
Hyperprolactinemia is a common disease of the hypothalamic pituitary unit. In recent years, due to the progress of diagnostic and therapeutic methods, many patients have returned to normal menstruation and become pregnant. This article reports 80 cases of hyperprolactinemia from May 1981 to October 1985, including 28 cases of pituitary tumors, 48 cases of functional hyperprolactinemia, and 4 cases of drug-induced causes. After treatment with bromocriptine, triads, clomiphene, hMG+hCG, surgery or radiation, 74 cases (92%) recovered from menstruation and 44 cases of pregnancy. The pregnancy rate was 66.1%, 8 cases of miscarriage. There is a case of galactorrhea-menopause syndrome. After surgical removal of pituitary tumors and radiation therapy, hypopituitarism produces hypogonadism amenorrhea. Twin pregnancy was obtained after treatment with hMG+hcG. Therefore, for the cause of treatment can improve the efficacy of treatment.