Syntheses and Anti-lung Cancer Effects of Two Novel Dy(Ⅲ) Complexes Based on 1,3,5-Benzenetricarbocy

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The reactions of 1,3,5-benzenetricarbocylic acid(H3BTC) and 1,3,5-benzenetrisbenzoic acid(H3BTB) with Dy(NO3)3·6H2O afford two novel Dy(III) coordination polymers respectively, Dy(BTC)(H_2O)DMF(1) and [Dy(BTB)(Et OH)](DMF)(2)(DMF = N,N-dimethylformamide). 1 shows a 3D framework composed of available Lewis-acid metal sites which are occupied by the coordinated water molecules, and 2 features a noninterpenetrated open 3D framework with a 5-connected bnn hexagonal topology possessing the point symbol(46.64). In addition, in vitro antitumor activities of compounds 1 and 2 on three human lung cancer cells(H1975, HCC827 and A549) were further determined. The reactions of 1,3,5-benzenetricarbocylic acid (H3BTC) and 1,3,5-benzenetrisbenzoic acid (H3BTB) with Dy (NO3) 3 · 6H2O afford two novel Dy H 2 O) DMF (1) and [Dy (BTB) (EtOH)] (DMF) (2) (DMF = N, N-dimethylformamide). 1 shows a 3D framework composed of available Lewis-acid metal sites which are occupied by the coordinated water molecules, and 2 features a noninterpenetrated open 3D framework with a 5-connected bnn hexagonal topology possessing the point symbol (46.64). In addition, in vitro antitumor activities of compounds 1 and 2 on three human lung cancer cells (H1975, HCC827 and A549) were further determined.
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