目的:比较不同终止妊娠时间的早发型重度子痫前期患者的妊娠结局,为临床选择最佳终止妊娠时机提供依据。方法:采用回顾性分析的方法对2009～2011年122例早发型重度子痫前期患者的临床资料进行分析,按终止妊娠的孕周分为3组:A组39例(≤32周分娩),B组42例(32～33+6周分娩),C组41例(≥34周分娩),对3组患者的各项临床指标、并发症及妊娠结局进行对比。结果:胎儿生长受限和颅内出血在A、C组间有明显统计学差异(P<0.05),C组胎死宫内和围生儿死亡率均为4.9%,较A、B组发生率低(P<0.05)。DIC、胎盘早剥、心力衰竭、子痫发作、低蛋白血症等方面各组间比较无统计学差异(P>0.05)。C组总体并发症发生率为95.1%,明显高于A组(P<0.05)。结论:早发型重度子痫前期患者孕32周后分娩,围产儿死亡率明显下降,妊娠结局良好。 Objective: To compare the pregnancy outcomes of patients with early-onset severe preeclampsia with different termination of pregnancy, and to provide the basis for choosing the best timing of termination of pregnancy. Methods: The clinical data of 122 patients with early-onset severe preeclampsia from 2009 to 2011 were analyzed retrospectively. According to the gestational age at termination of pregnancy, the patients were divided into three groups: 39 patients (≤32 weeks delivery) in group A, Forty-two patients in group B (32-33 + 6 weeks delivery) and 41 patients in group C (≥34 weeks delivery) were enrolled in this study. Clinical data, complications and pregnancy outcomes were compared between the three groups. Results: Fetal growth restriction and intracranial hemorrhage were significantly different between groups A and C (P <0.05). The intrauterine and perinatal mortality rates in group C were 4.9%, which were significantly lower than those in groups A and B Low (P <0.05). DIC, placental abruption, heart failure, eclampsia, hypoproteinemia and other aspects between the groups showed no significant difference (P> 0.05). The overall complication rate in group C was 95.1%, which was significantly higher than that in group A (P <0.05). Conclusion: Early onset severe preeclampsia patients delivered after 32 weeks pregnant, perinatal mortality decreased significantly, the pregnancy outcome was good.