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凝血酶诱导的Ca~(2+)流动在血小板的分泌和聚集中起着重要的作用。本文发现一种广谱蛋白酶抑制剂抑肽酶能抑制凝血酶诱导的血小板中Ca~(2+)的流动:(1)当胞外存在0.5mmol/LCa~(2+)时,抑肽酶抑制凝血酶(0.1
Thrombin-induced Ca 2+ flow plays an important role in platelet secretion and aggregation. This article found that a broad-spectrum protease inhibitor aprotinin can inhibit thrombin-induced Ca ~ (2+) flow in platelets: (1) when extracellular 0.5mmol / LCa ~ (2+), aprotinin Inhibition of thrombin (0.1