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目的:比较慢性牙周炎患者与牙周健康者血浆钙结合蛋白水平的差异。方法:57例慢性牙周炎患者和48例牙周健康者,空腹抽取静脉血。采用酶联免疫吸附方法测定血浆中钙结合蛋白水平,比较两组的差异,并分析血浆钙结合蛋白与体重指数、各项牙周临床参数之间的相关关系。结果:慢性牙周炎患者血浆钙结合蛋白水平为(1.85±0.81)mg/L,高于健康对照组的(1.57±0.77)mg/L,但无显著性P=0.076。慢性牙周炎患者血浆钙结合蛋白与体重指数,出血指数,探诊深度和附着丧失未见明显的正相关关系(相关系数r及P值分别为0.145,0.178,0.260,0.242和0.282,0.185,0.051,0.069)。结论:未发现慢性牙周炎对血浆钙结合蛋白水平的影响。
Objective: To compare the difference of plasma calcium binding protein between patients with chronic periodontitis and periodontal health. Methods: 57 cases of chronic periodontitis and 48 cases of periodontal health, fasting venous blood. The levels of calcium-binding protein in plasma were determined by enzyme-linked immunosorbent assay (ELISA), the differences between the two groups were compared, and the correlation between plasma calcium-binding protein and body mass index and various periodontal parameters was analyzed. Results: The level of plasma calcium-binding protein in patients with chronic periodontitis was (1.85 ± 0.81) mg / L, which was significantly higher than that of healthy controls (1.57 ± 0.77) mg / L, but no significant P = 0.076. Chronic periodontitis plasma calcium-binding protein and body mass index, bleeding index, exploration depth and attachment loss no significant positive correlation (correlation coefficient r and P values were 0.145,0.178,0.260,0.242 and 0.282,0.185, 0.051, 0.069). Conclusion: No effect of chronic periodontitis on plasma calcium-binding protein levels was found.