Crohn氏病在肠道外出现症象较为常见,但发生于口咽部者很少,发生率在6～20％之间,少数口咽部的病损可先于肠道出现。其发病机理尚不清楚,可能与唾液中IgA降低及口内免疫抗原引起体液或/和细胞免疫敏感性增高有关。本病在口腔部的表现包括阿弗它溃疡、唇炎并有裂口,或呈散布的卵石样病损,具有炎性增生和裂隙,乃至在口腔前庭及磨牙后粘膜出现息肉样损害和边缘增厚的较深的线状溃疡。本病发生于口咽部者表现亦多种多样,应与肿瘤,类肉瘤 Crohn’s disease is more common in the extraintestinal tract, but it rarely occurs in the oropharynx. The incidence rate is between 6 and 20%. A small number of oropharyngeal lesions may occur before the intestine. The pathogenesis is still unclear, which may be related to the decrease of IgA in saliva and the increase of humoral and/or cellular immune susceptibility caused by intra-oral immunization antigens. The disease’s performance in the oral cavity includes aphthous ulcers, cheilitis, and fissures, or scattered pebble-like lesions, inflammatory hyperplasia and fissures, and polypoid lesions and marginal enlargement in the oral vestibule and post-molar mucosa. Thick, deep, linear ulcers. Occurrence of this disease in the oropharynx is also diverse and should be associated with tumors and sarcomas