论文部分内容阅读
目的了解在新生儿缺氧缺血性脑病(HIE)恢复期使用神经营养药对患儿智能及运动发育的影响。方法将100例3个月内的HIE患儿随机分为药物组和对照组。药物组在1岁内进行神经发育训练及定时应用神经营养药,对照组进行神经发育训练。1岁时应用CDCC方法对患儿进行发育评估,对比两组疗效。结果药物组患儿1岁时量表分智能发育指数为98.95±10.49,对照组为93.06±11.71,P<0.05,差异有显著性;药物组患儿1岁时运动发育指数为94.51±8.93,对照组为97.66±10.69,P>0.05,差异没有显著性。结论对HIE恢复期患儿,在坚持神经发育训练和家庭康复的基础上,早期联合应用神经营养药物,有利于患儿智能发育水平的提高,对运动发育水平改善不明显。
Objective To understand the effects of using neurotrophic drugs on the intelligence and motor development of neonates with hypoxic-ischemic encephalopathy (HIE) during the recovery period. Methods 100 cases of HIE in 3 months were randomly divided into drug group and control group. The neuropsychological training and neurotrophic drugs were applied to the drug group within 1 year of age and the control group were trained in neurodevelopment. At 1 year of age, CDCC method was used to evaluate the development of children, comparing the two groups. Results At 1 year of age, the index of mental development in the drug group was 98.95 ± 10.49, in the control group was 93.06 ± 11.71, P <0.05, the difference was significant. The index of motor development in the drug group was 94.51 ± 8.93 at 1 year old, The control group was 97.66 ± 10.69, P> 0.05, the difference was not significant. Conclusions The early combined application of neurotrophic drugs on the basis of neurodevelopmental training and family rehabilitation in children with convalescent HIE is beneficial to the improvement of intellectual development in children and to the improvement of motor development.