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目的 :为了解延安市不良孕产史妇女及妇科病患者与正常妊娠结局者及健康妇女的 Toxo感染情况 .方法 :用 ELISA对 96 4份血清进行了 Toxo特异性 Ig M、Ig G抗体的检测 .结果 :( 1 )延安市正常妊娠结局产妇和健康妇女 Toxo总阳性率为1 1 .1 9% . ( 2 )各不良妊娠结局组的 Toxo总感染率分别为 1 8.75 %、41 .1 1 %和30 .0 0 % ,均明显高于正常结局组 1 0 .82 % ,其中死胎、习惯性流产及难免流产组有显著差异 ( P<0 .0 1 ) . ( 3)妇科病患者中 ,不孕症和盆腔炎组 Toxo总感染率分别为2 8.33%和 2 3.2 6 % ,均明显高于健康妇女组 1 2 .0 5 % ( P<0 .0 1 ,P<0 .0 5 ) .结果 :上述结果与国内多数学者报道相一致 ,从而进一步证实 ,Toxo感染可导致不良的妊娠结局 ,同时更加说明 Toxo感染可能是妇科炎症性疾病及不孕症的致病原因之一
Objective: To understand the Toxo infection of poor pregnant women and gynecological patients with normal pregnancy outcome and healthy women in Yan’an City.Methods: Toxo-specific Ig M and Ig G antibodies were detected in 964 serum samples by ELISA .Results: (1) The positive rate of Toxo in normal pregnant women and healthy women in Yan’an City was 11.1%. (2) The total infection rates of Toxo in each group with adverse pregnancy were 1 8.75%, 41.1 1 % And 30.0%, respectively, were significantly higher than those in the normal group (0.82%), of which there was significant difference between stillbirth, habitual abortion and inevitable abortion (P <0.01). (3) Among gynecological patients , Infertility and pelvic inflammatory disease group Toxo infection rates were 2 8.33% and 2 3.2 6%, were significantly higher than the healthy women group 12.5% (P <0 01, P <0 05 ) .Results: The above results are consistent with most domestic scholars to further confirm that Toxo infection can lead to poor pregnancy outcomes, and more shows that Toxo infection may be one of the causes of gynecological inflammatory diseases and infertility