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目的:探讨低位直肠癌术前大剂量放射治疗的疗效。方法:42例低位直肠癌患者联合术前大剂量放疗为治疗组,同期外科单纯手术40例为对照组。结果:治疗组与对照组局部复发率分别为:14.2%(6/42)、35%(14/40),χ2=4.76,P<0.05,两组比较差异有显著意义。治疗组与对照组5a生存率分别为76.2%(32/42)、57.5%(23/40),χ2=9.64,P<0.05,两组比较差异有显著意义。结论:低位直肠癌术前给予大剂量放疗可以提高5a生存率,值得临床应用。
Objective: To investigate the effect of preoperative high dose radiation therapy for low rectal cancer. Methods: 42 patients with low rectal cancer combined with preoperative high-dose radiotherapy for the treatment group, the same period surgery alone 40 cases of the control group. Results: The local recurrence rates in treatment group and control group were 14.2% (6/42), 35% (14/40), χ2 = 4.76, P <0.05, respectively. There was significant difference between the two groups. The survival rates of treatment group and control group 5a were 76.2% (32/42), 57.5% (23/40) respectively, and χ2 = 9.64, P <0.05. There was significant difference between the two groups. Conclusion: Low-dose preoperative radiotherapy for low rectal cancer can improve the survival rate of 5a, which is worthy of clinical application.