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观察６６例不同病期肾病综合征（ＮＳ）患儿血清钙离子（ＩＣａ）、骨钙素（ＢＧＰ）、尿Ⅰ型胶原交联氨基末端肽（ＮＴＸ）、骨密度（ＢＭＣ）及腕骨Ｘ线变化。结果表明：①ＮＳ患儿存在骨代谢异常；②在反映骨代谢变化时，ＢＧＰ及ＮＴＸ较ＢＭＣ、Ｘ线摄片敏感，可作为肾性骨病早期改变的观察指标
Sixty-four children with nephrotic syndrome (NS) at different stages were observed for serum calcium (ICa), BGP, urine NTX, BMC and carpal X-ray Variety. The results showed that: (1) bone metabolism was abnormal in children with NS; (2) BGP and NTX were more sensitive than BMC and X-ray in reflecting the changes of bone metabolism, which could be used as an indicator of early changes of renal osteodystrophy