自1986年Barker等[1]提出“成人疾病的宫内起源学说(Fetal Origin of Adult Disease)”以来,对生命早期的生长发育与成人期疾病关系的研究在全世界范围内取得了长足的进展。胎儿宫内营养和发育状况与出生后的健康状况息息相关。出生体重是反映宫内生长情况的重要的可测量指标,巨大儿可能是胎儿在母体内因某些诱因而体重过度增长的体现。我国一般将出生体重达到或超过4kg作为巨大儿的判断标准[2](国外也 Since Barker et al. [1] proposed “the Fetal Origin of Adult Disease” in 1986, the study of the relationship between early life growth and adult disease has made great progress worldwide Progress. Intrauterine fetal nutrition and development status are closely related to the health status after birth. Birth weight is an important measurable indicator of intrauterine growth, and macrosomia may be an indication of fetal over-growth due to certain causes in the mother’s body. China’s general birth weight will reach or exceed 4kg as a huge child’s judgment [2] (foreign also