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使用抗菌剂后总面临产生耐药菌株的问题。有时一种新的抗菌剂投入使用可立即出现耐药菌株,但在大多数情况下,耐药菌株在使用几年后才出现。洗必太是一种广谱抗菌剂,广泛用于牙科和其它科的治疗中。长期使用洗必太会产生变形链球菌耐药菌株,但短期使用后变形链球菌发生耐药性的情况未见报道。本研究采用三种不同的洗必太治疗牙齿方案,观察一周内用药唾液中变形链球菌对抗菌剂的敏感性。 随机将唾液中变形链球菌计数在10~5CFU/ml及以上的58名自愿者分成三组。第一组19人,用40％洗
The use of antimicrobials always faces the problem of producing drug-resistant strains. Sometimes a new antibacterial agent is put into use immediately resistant strains, but in most cases, resistant strains appear only after several years of use. Chlorhexidine is a broad spectrum antibacterial agent that is widely used in the treatment of dentistry and other subjects. Long-term use must wash will produce mutans Streptococcus mutans resistant strains, but after short-term use of Streptococcus mutans resistance has not been reported. In this study, three different chlorhexidine tooth treatment programs were used to investigate the sensitivity of S. mutans to antibacterial agents in saliva during one week. Fifty-eight volunteers randomly assigned to S. mutans in saliva between 10 and 5 CFU / ml were divided into three groups. The first group of 19 people, wash with 40%