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Objective To investigate the chemical constituents from Aidi Injection.Methods The chemical constituents were isolated by chromatography on Sephadex LH-20 gel columns and reverse phase semi-preparative HPLC repeatedly.Their structures were identified by spectroscopic analysis(NMR and MS).Results Twenty-two compounds were isolated and identified to be 3-O-3′,4′-diacetyl-β-D-xylopyranosyl-6-O-β-D-glucopyranosyl- cycloastragenol(1),astragaloside IV(2),astragaloside II(3),astragaloside I(4),isoastragaloside I(5), acetylastragaloside I(6),ginsenosid Re(7),ginsenoside Rf(8),ginsenoside Rg1(9),ginsenoside Rb3(10), notoginsenoside R4(11),ginsenoside Rb1(12),ginsenoside Rc(13),ginsenoside Rb2(14),ginsenoside Rd(15), lucyoside H(16),3-O-β-D-glucopyranosyl(1→4)-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-α-L- arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside (17),3-O-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl[β-D-glucopyranosyl-(1→4)]-(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-arabinopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(18),syringin (19),elentheroside E(20),4-(1,2,3-trihydroxypropyl)-2,6-dimethoxyphenyl-1-O-β-D-glucopyranoside(21),and coniferin(22).Conclusion Compounds 1-6 are originated from Astragalus membranceus,compounds 7-18 are originated from Panax ginseng,and compounds 19-22 are originated from Acanthopanax senticosus by LC-MS analysis.Compound 1 is a new compound.
Objective To investigate the chemical constituents from Aidi Injection. Methods The chemical constituents were isolated by chromatography on Sephadex LH-20 gel columns and reverse phase semi-preparative HPLC. Their structures were identified by spectroscopic analysis (NMR and MS). Results Twenty- Two compounds were isolated and identified to be 3-O-3 ’, 4’-diacetyl-β-D-xylopyranosyl-6-O-β- D-glucopyranosyl-cycloastragenol (1), astragaloside IV (2), astragaloside II 3, astragaloside I (4), isoastragaloside I (5), acetylastragaloside I (6), ginsenosid Re (7), ginsenoside Rf (8), ginsenoside Rgl (9), ginsenoside Rb3 (10), notoginsenoside R4 , ginsenoside Rb1 (12), ginsenoside Rc (13), ginsenoside Rb2 (14), ginsenoside Rd (15), lucyoside H (16), 3-O-β-D-glucopyranosyl glucopyranosyl (1 → 3) -α-L-rhamnopyranosyl (1 → 2) -α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl -β-D-glucopyranoside (17), 3-O-β-D-glucopyranosyl (1 → 3) -α-L-rhamnopyranosyl β-D-glucopyranosyl- (1 → 4)] - (1 → 2) -α-L-arabinopyranosyl oleanolic acid 28-O-α-L-arabinopyranosyl (1 → 4) 6) -β-D-glucopyranoside (18), syringin (19), elentheroside E (20), 4- (1,2,3- trihydroxypropyl) -2,6-dimethoxyphenyl-1-O-β-D-glucopyranoside (21), and coniferin (22). Conlusion compounds 1-6 are originated from Astragalus membranceus, compounds 7-18 are originated from Panax ginseng, and compounds 19-22 are originated from Acanthopanax senticosus by LC-MS analysis. Compound 1 is a new compound.