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尽管已意识到端粒酶可能是目前已知特异性最好的肿瘤标志，但端粒酶的临床应用迄今未能得以普及推广，其原因之一是人端粒酶的蛋白组份仍不十分清楚．为此，我们利用端粒酶核糖核蛋白的特性，尝试建立一种亲和纯化人端粒酶的手段，以期获得具有完整活性的亲和纯人胃癌端粒酶并
Although it is recognized that telomerase may be the best known tumor marker, the clinical application of telomerase has not been popularized so far. One of the reasons is that the human telomerase protein composition is still not very good. clear. To this end, we used the characteristics of telomerase ribonucleoproteins to try to establish a means of affinity purification of human telomerase in order to obtain a fully active affinity human gastric cancer telomerase.