新生儿缺氧缺血性脑病(Hypoxic-ischemicencephalopathy,HIE)是指各种围生期窒息引起的部分或完全缺氧,引发脑血流减少或暂停而导致胎儿或新生儿的脑损伤。其发病率、致残率、病死率较高,除有神经系统症状外,可伴多脏器损害,以心肌损害较常见,发生率约为28%~44%,甚至高达65.5%[1],预后差异较大,且可加重脑损伤[2],早期 Hypoxic-ischemic encephalopathy (HIE) refers to a variety of perinatal asphyxia caused by partial or complete hypoxia, causing cerebral blood flow reduction or pause caused by fetal or neonatal brain damage. Its morbidity, morbidity and mortality are high, with the exception of neurological symptoms, may be associated with multiple organ damage, myocardial damage is more common, the incidence of about 28% to 44%, or even up to 65.5% [1] , A greater difference in prognosis, and may increase brain damage [2], early