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广东省是我国α地中海贫血高发地区之一,作者曾对有α地中海贫血特征者11例,从新生儿期追踪观察至8月～11/2岁,发现多数患者有轻度贫血和红细胞形态学不同程度的改变,临床难以与体内缺铁所致的红细胞生成缺铁期和缺铁性贫血相鉴别。本文目的在观察红细胞内游离原卟啉含量变化对α地中海贫血特征的诊断及其与缺铁性贫血的鉴别诊断意义。
Guangdong Province is one of the high incidence of α-thalassemia in China. The authors have 11 cases with the characteristics of α-thalassemia from follow-up in neonatal period to August to 11/2 years old and found that most patients had mild anemia and red blood cell morphology Different degrees of change, difficult to clinically and iron deficiency caused by the formation of erythrocyte iron deficiency and iron deficiency anemia differentiate. This article aims to observe the changes of intracellular free protoporphyrin content in the diagnosis of α-thalassemia characteristics and its differential diagnosis with iron deficiency anemia.