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目的了解四川省大骨节病病情。方法随机抽取6个大骨节病活跃病区县进行儿童右手X线检查和成人大骨节病病情调查,采集儿童发样及当地主食粮样进行硒含量检测。结果①儿童X线检出率平均4.86%(0.96%～6.93%);②成人大骨节病平均患病率32.10%,其中Ⅰ度患病率17.2%,Ⅱ度患病率10.2%,Ⅲ度患病率4.8%;各地区中若尔盖患病率最高,达50%,壤塘、色达、阿坝、旺苍、汉源患病率分别为41.0%、33.3%、30.4%、24.4%、15.8%;③儿童发硒水平平均为0.270±0.079mg/kg;④粮食硒含量平均为0.0123±0.0102mg/kg。结论所调查地区儿童大骨节病病情处于控制或基本控制范围,但仍然有新发,成人大骨节病病情较为严重。
Objective To understand the condition of Kashin-Beck disease in Sichuan Province. Methods Six randomly selected districts with active KBD were enrolled in the investigation of right X-ray and adult KBD in children. Selenium content was detected in children samples and local staple food samples. Results ① The average detection rate of X-ray in children was 4.86% (0.96% ~ 6.93%). ② The average prevalence of adult KBD was 32.10%, of which the prevalence was 17.2% in Ⅰ, 10.2% in Ⅱ and Ⅲ The prevalence rate in Zoige was the highest in all regions (50%). The prevalence rates of Zodiac, Seda, Aba, Wangcang and Hanyuan were 41.0%, 33.3%, 30.4%, 24.4% and 15.8 %; ③ children selenium average level of 0.270 ± 0.079mg / kg; ④ grain selenium content average of 0.0123 ± 0.0102mg / kg. Conclusion The prevalence of Kashin-Beck disease in children in the surveyed areas is in the control or basic control range, but new cases are still occurring. The prevalence of adult Kashin-Beck disease is more serious.