新生儿缺氧缺血性脑病(HIE)是新生儿窒息后的严重并发症,发病率和死亡率较高,常留下永久性神经功能障碍。我院儿科在传统治疗的基础上加用纳洛酮治疗中、重度HIE,获得了显著疗效。1 资料与方法1.1 病例选择为1998年4月～2000年4月收住我院儿科的中、重度HIE患儿,均符合HIE的临床诊断及分度标准,并在入院 48h内经颅脑 B超及 CT确诊者共 82例。随 Neonatal hypoxic-ischemic encephalopathy (HIE) is a serious complication after neonatal asphyxia, with a high morbidity and mortality, often leaving permanent neurological dysfunction. Pediatric hospital in the traditional treatment based on the use of naloxone in the treatment of moderate and severe HIE, obtained a significant effect. 1 Materials and Methods 1.1 Case Selection April 1998 ~ April 2000 admitted to our hospital pediatric patients with moderate and severe HIE are in line with the clinical diagnosis and classification of HIE standard and within 48 hours after admission by the brain B ultrasound And CT confirmed a total of 82 cases. With