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目的比较肝动脉化疗栓塞术(TACE)联合手术、TACE联合射频消融术(RFA)与单独TACE或RFA治疗中晚期肝癌的疗效。方法对375例原发性肝癌患者分别采用TACE联合手术、TACE联合RFA与单独TACE或RFA治疗。结果接受以RFA为主治疗的107例患者,1、3、5年生存率分别为64.8%、36.7%、28.9%;176例以TACE为主的综合治疗,1、3、5年生存率分别为70.1%、30.8%、19%;32例患者接受TACE后,行Ⅱ期手术治疗,1、3、5年生存率分别为97%、80.9%、45%;60例患者接受TACE联合RFA治疗,1、3、5年生存率分别为99%、72.0%、37%。结论 TACE联合手术治疗以及TACE联合RFA治疗原发性肝癌的疗效较单独TACE或者RFA治疗效果好。
Objective To compare the efficacy of transcatheter arterial chemoembolization (TACE) with surgery, TACE combined with radio-frequency ablation (RFA) and TACE or RFA alone in the treatment of advanced liver cancer. Methods 375 patients with primary liver cancer were treated with TACE combined with TACE and RFA with TACE or RFA alone. Results The survival rates of one, three and five years were 64.8%, 36.7% and 28.9% respectively in 107 patients treated with RFA. The comprehensive treatment with TACE was 176 cases and the survival rates of 1,3 and 5 years were , 70.1%, 30.8% and 19% respectively. After TACE was performed in 32 patients, the survival rates at 1, 3 and 5 years were 97%, 80.9% and 45% respectively after receiving TACE. 60 patients underwent TACE combined with RFA The 1, 3, 5 year survival rates were 99%, 72.0% and 37% respectively. Conclusion TACE combined with surgical treatment and TACE combined with RFA in the treatment of primary liver cancer curative effect than TACE alone or RFA treatment effect.