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目的观察外用盐酸氨酮戊酸散光动力联合注射重组人干扰素α2b治疗并预防尖锐湿疣复发的临床效果。方法收集医院诊治的尖锐湿疣患者60例为研究对象,随机分为观察组和对照组,每组30例。对照组给予高频电离子切割治疗,同时联合应用重组人干扰素α2b治疗;观察组给予外用盐酸氨酮戊酸散光动力法治疗,并联合使用重组人干扰素α2b治疗。观察比较2组患者治愈率、疣体一次性清除率;随访6个月统计2组患者尖锐湿疣复发率。结果观察组一次性清除率达90.00%,高于对照组的63.33%(P<0.05);观察组治愈率为90.00%,高于对照组的50.00%(P<0.01);随访统计发现,观察组患者复发率为10.00%,低于对照组的50.00%(P<0.01)。结论外用盐酸氨酮戊酸散光动力疗法对尖锐湿疣患者一次性病灶清除率高,联合注射用重组人干扰素α2b能有效预防尖锐湿疣复发,值得临床上推广应用。
Objective To observe the clinical effect of external use of amion acylate coumarin combined with injection of recombinant human interferon α2b in the prevention and treatment of recurrence of condyloma acuminatum. Methods Sixty patients with condylomata acuminatum who were diagnosed and treated in our hospital were collected and randomly divided into observation group and control group, 30 cases in each group. The control group was treated by high-frequency iontophoresis and combined with recombinant human interferon α2b. The observation group was treated with exenatide aspirin astigmatism and combined with recombinant interferon α2b. Observe and compare the cure rate of two groups of patients, wart one-time clearance rate; follow-up 6 months, two groups of patients with recurrent condyloma acuminata. Results The one-time clearance rate of the observation group was 90.00%, which was higher than that of the control group (63.33%, P <0.05). The cure rate of the observation group was 90.00%, which was higher than that of the control group (50.00%, P <0.01) The recurrence rate was 10.00% in the group, which was lower than 50.00% in the control group (P <0.01). Conclusions External use of amion acylate hydrochloride astigmatism therapy in patients with condyloma acuminatum lesions of high clearance, combined with recombinant interferon α 2b can effectively prevent the recurrence of condyloma acuminata, it is worth promoting the clinical application.