采用切除胸腺瘤治疗各型重症肌无力(MG)46例,病理证实胸腺瘤15例,恶性胸腺瘤31例,伴异位胸腺增生1例。术后52.2％的病例发生了MG危象,其危象见于Ⅱ_B和Ⅲ型病例。10.9％的病例在院死亡。术后讨39例病人进行了6个月～12年的随访,症状缓解33.3％,改善20.5％,无变化2.6％,与本病有关的死亡者为38.5％,MG合并胸腺瘤病例术后MG危象发生率高,围手术期和离院后死亡率亦较高。近年来对病情危重病例胸腺瘤切除早期行气管切开,酌情辅助呼吸,是预防和治疗MG危象的重要方法,有助于降低围手术期死亡率。 Forty-six cases of myasthenia gravis (MG) were treated by resection of thymoma. Fifteen cases of thymoma, 31 cases of malignant thymoma and 1 case of ectopic thymic hyperplasia were confirmed by pathology. After 52.2% of cases of MG crisis occurred, the crisis seen in Ⅱ B and Ⅲ cases. 10.9% of the cases died at the hospital. Thirty-nine patients were followed up for 6 months to 12 years. The symptoms were relieved 33.3%, improved 20.5%, unchanged 2.6%, and 38.5% of the deaths related to this disease. MG patients with postoperative MG of thymoma The high incidence of crisis and perioperative and post-hospital mortality is also higher. In recent years, critically ill patients with thymoma resection of early tracheotomy, as appropriate, assisted breathing is an important method to prevent and treat MG crisis, help to reduce perioperative mortality.