半胱氨酸组织蛋白酶S(Cathepsin S,Cat S)属于溶酶体蛋白酶,在中枢神经系统有着广泛、重要的生理功能,尤其是其在胞外基质降解和胞内抗原提呈中所起的重要作用。Cat S的这些功能和多种神经系统疾病的病理生理机制密切相关,深入阐明Cat S在神经系统疾病理生理机制中的作用具有重要的意义。 Cathepsin S (Cat S) is a lysosomal protease that has a wide range of important physiological functions in the central nervous system, in particular its role in extracellular matrix degradation and intracellular antigen presentation Important role. These functions of Cat S are closely related to the pathophysiological mechanisms of a variety of neurological diseases. It is of great significance to clarify the role of Cat S in the pathogenesis of neurological diseases.