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报道新型强心药咪苯嗪酮的合成。对酰化、缩合两步的反应条件进行了改进。药理实验结果表明它具有明显的抗血栓作用,并可能选择性抑制血栓素A_2合成酶。
Report new cardiomodulators imidazinone synthesis. The acylation, condensation reaction conditions were improved. Pharmacological results show that it has obvious antithrombotic effect, and may selectively inhibit thromboxane A_2 synthase.