例1 男,65岁。患者于入院前二个月在左大腿等处出现龙眼大小的结节,与皮肤粘连、无痛痒。经病理活检示“炎症性肉芽肿,巨噬细胞内可见真菌菌丝”,皮肤结节取材作墨汁染色直接镜检,以及真菌培养与动物接种证实为“新生隐球菌”。入院后常规胸部X线检 Example 1 male, 65 years old. Patients in the left thigh two months before admission, the size of the longan nodules appear, with the skin adhesion, no itching. Pathological biopsy showed “inflammatory granuloma, macrophages visible fungal mycelium,” skin nodules drawn for ink stain direct microscopy, and fungal culture and animal vaccination confirmed as “Cryptococcus neoformans.” After admission, routine chest X-ray examination