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目的系统评价根管治疗术一次法与多次法治疗感染根管的治愈率。方法计算机检索PubMed、EMbase、EBSCO、MEDLINE、The Cochrane Library(2015年第3期)、CNKI、VIP、CBM和WanFang Data数据库,搜集根管治疗术一次法与多次法比较治疗感染根管的相关随机对照试验(RCT),检索时限均从建库至2015年3月。由2位评价员独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用RevMan 5.3.5软件进行Meta分析。结果共纳入9个RCT,共1 146颗患牙。Meta分析结果显示:在根管治疗术治疗感染根管的治愈率方面,一次法为88.98%,多次法为85.61%,两组差异无统计学意义[OR=1.36,95%CI(0.95,1.96),P=0.09]。结论基于当前可得证据,根管治疗术一次法与多次法治疗感染根管的治愈率相当。受纳入研究数量所限,上述结论尚需开展更多高质量研究予以验证。
Objective To systematically evaluate the cure rate of root canal therapy by root canal therapy and primary method. Methods The databases of PubMed, EMbase, EBSCO, MEDLINE, The Cochrane Library (2015), CNKI, VIP, CBM and WanFang Data were searched by computer. The correlations between primary root canal therapy and multiple root canal therapy Randomized controlled trial (RCT), search time from the database to March 2015. After two reviewers independently screened the literature, extracted data, and assessed the risk of being included in the study, the Meta-analysis was performed using RevMan 5.3.5 software. Results A total of 9 RCTs were included, with a total of 1,146 teeth. The results of Meta analysis showed that the primary cure rate was 88.98% and the multiple test was 85.61% in root canal therapy for root canal infection. There was no significant difference between the two groups [OR = 1.36,95% CI (0.95, 1.96), P = 0.09]. Conclusions Based on the current available evidence, root canal treatment of primary and multiple treatment of infected root canal cure rate quite. Due to the limited number of studies involved, the above conclusion still needs more high-quality research to be verified.