目的分析铁岭市2010—2014年人间布氏菌病流行特征,为布氏菌病防治提供科学依据。方法对医疗系统报告的布氏菌病例进行流行病学调查,设立布病主动监测点,在监测点进行摸底调查,随机抽取人群开展血清流行病学调查,对报告和监测的确诊病例,用描述流行病学方法进行特征分析。结果铁岭市2010—2014年共确诊布病322例,年均发病率为2.13/10万,其中报告病例确诊感染者258例,病例64人;主动监测共调查10 676人,其中2 152人进行血清学检测,阳性84人,阳性率为3.90%,确诊病例占全部确诊病例的19.88%,监测点内确诊132例,监测点外确诊190例,年发病率比较差异显著(χ2=11.53,P<0.05)。7个县(市、区)均有布病病例报告,年均报告发病率居前三位的县区分别是西丰县、铁岭县、开原市,各县(市、区)发病率差异显著(χ2=60.68,P<0.05)。发病主要集中于4—8月,呈现出明显的季节性。322例病例中,男性241例,占74.84%;女性81例,占25.16%。,男女性别比为2.98:1。发病主要集中在30~60年龄组,发病281例,占发病总例数的87.27%。职业为农民283例,占总数的87.89%。结论铁岭市人间布病疫情呈上升趋势,疫情范围广泛,高度散发。建议加大布病防控知识的宣传普及,提高民众的自我防护意识。 Objective To analyze the epidemic characteristics of human brucellosis in Tieling from 2010 to 2014, and provide a scientific basis for the prevention and treatment of brucellosis. Methods The epidemiological investigation of brucellosis cases reported in the medical system was carried out. Active surveillance sites for brucellosis were established, and thoroughly surveyed at monitoring sites. Serum epidemiological surveys were randomly selected from the population. The reported and monitored confirmed cases were described by Epidemiological methods were used for characterization. Results A total of 322 cases of brucellosis were diagnosed in Tieling City from 2010 to 2014, with an average annual incidence rate of 2.13 per 100 000. Among them, 258 cases were confirmed and 64 cases were reported. A total of 10 676 persons were surveyed actively, of whom 2 152 Serological test, 84 were positive, the positive rate was 3.90%, diagnosed cases accounted for 19.88% of all confirmed cases, 132 cases were diagnosed within the monitoring point, 190 cases were diagnosed outside the monitoring point, the annual incidence was significantly different (χ2 = 11.53, P <0.05). There were cases of brucellosis in 7 counties (cities and districts), and the top three counties in the annual report were Xifeng County, Tieling County, Kaiyuan City and counties (cities and districts), respectively. The incidence rates were significantly different χ2 = 60.68, P <0.05). The incidence mainly concentrated in April-August, showing a clear seasonal. Of 322 cases, 241 were male, accounting for 74.84%; 81 were female, accounting for 25.16%. , The male to female ratio was 2.98: 1. The incidence mainly concentrated in the 30 to 60 age group, 281 cases of disease, accounting for 87.27% of the total number of cases. Occupation of 283 farmers, accounting for 87.89% of the total. Conclusion Tieling City, the epidemic of human brucellosis is on the rise, the epidemic is widespread and highly distributed. It is suggested to increase the popularization of the knowledge on the prevention and control of brucellosis and to raise public awareness of self-protection.