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目的:探讨白细胞(WBC)计数与代谢综合征(MS)及其亚组分的关系。方法:对662例重庆地区成年人测定了血糖、血脂、胰岛素、WBC计数、超敏C反应蛋白(hsCRP)等指标,根据2005年IDF标准诊断MS。结果:有MS者WBC计数明显高于无MS者(P<0.01),且WBC计数增高与肥胖、高血压、高血糖、高甘油三酯血症等MS亚组分均有关。根据WBC计数的四分位数,将受试者分为4组,结果提示随着WBC水平增加,腰围、BMI、SBP、DBP、TG、TC、LDL-C、HomaIR、hsCRP增高(P<0.01),而HDL-C水平降低(P<0.01)。结论:WBC计数作为炎症标志物,与MS及其亚组分关系密切,WBC计数增高可能是MS发生的标志之一。
Objective: To investigate the relationship between white blood cell count (WBC) and metabolic syndrome (MS) and its sub-components. Methods: 662 adults in Chongqing were tested for blood glucose, lipids, insulin, WBC count and hsCRP, and MS was diagnosed according to the 2005 IDF criteria. Results: The WBC count of MS patients was significantly higher than that of no MS patients (P <0.01), and the increase of WBC count was associated with MS subcomponents such as obesity, hypertension, hyperglycemia and hypertriglyceridemia. According to the quartiles of WBC count, the subjects were divided into 4 groups. The results indicated that the waist circumference, BMI, SBP, DBP, TC, LDL-C, HomaIR and hsCRP increased with the increase of WBC level ), While HDL-C levels decreased (P <0.01). Conclusion: WBC count as a marker of inflammation is closely related to MS and its sub-components. WBC count may be one of the markers of MS.