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目的:分析肺癌术后应用低分子肝素预防深静脉血栓(DVT)和肺栓塞(PE)的疗效和安全性。方法:将400例患者随机分为实验组和对照组,各200例,实验组术后应用低分子肝素抗凝治疗,记录两组相关临床指标和治疗效果。结果:实验组较对照组DVT和PE的发生率明显减低;术后引流量、出血事件、凝血指标无统计学差异。结论:低分子肝素降低肺癌术后DVT和PE的发生率,不增加出血的风险,临床应用安全有效。
Objective: To analyze the efficacy and safety of low molecular weight heparin in preventing postoperative deep venous thrombosis (DVT) and pulmonary embolism (PE). Methods: 400 patients were randomly divided into experimental group and control group, 200 cases each. The experimental group received low molecular weight heparin anticoagulation after operation, and the related clinical indexes and therapeutic effects were recorded. Results: The incidences of DVT and PE in the experimental group were significantly lower than those in the control group. There was no significant difference in postoperative drainage, bleeding and coagulation indexes. Conclusions: Low molecular weight heparin can reduce the incidence of postoperative DVT and PE in lung cancer without increasing the risk of bleeding, and its clinical application is safe and effective.