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目的探讨对原发性肝癌术后早期肝内复发转移患者采用介入治疗的临床效果。方法收集2012年10月—2014年10月收治的原发性肝癌术后早期肝内复发转移患者60例,按照随机、对照、双盲的原则随机分成对照组与研究组,每组各30例。对照组给予5-氟尿嘧啶与奥沙利铂联合化疗治疗,研究组给予5-氟尿嘧啶与奥沙利铂联合进行介入治疗。观察和比较两组患者的治疗效果、不良反应发生情况。结果研究组治的总有效率显著高于对照组(P<0.05),研究组患者的不良反应发生率显著低于对照组,术后1年生存率显著高于对照组(P<0.05)。结论对原发性肝癌术后早期肝内复发转移患者采用介入治疗方案进行治疗疗效显著,可有效减少患者的不良反应,提高患者的生存率,值得推广。
Objective To investigate the clinical effect of interventional therapy on patients with primary liver cancer with early postoperative recurrence and metastasis. Methods Sixty patients with primary intrahepatic metastasis and recurrence of primary liver cancer who were admitted to our hospital from October 2012 to October 2014 were randomly divided into control group and study group according to the principle of randomized, controlled and double-blind, with 30 cases in each group . The control group was given 5-fluorouracil and oxaliplatin combined with chemotherapy, the study group given 5-fluorouracil combined with oxaliplatin for interventional therapy. Observed and compared the treatment effect of two groups of patients, the incidence of adverse reactions. Results The total effective rate of the study group was significantly higher than that of the control group (P <0.05). The adverse reaction rate of the study group was significantly lower than that of the control group. The 1-year survival rate was significantly higher than that of the control group (P <0.05). Conclusion The treatment of primary liver cancer patients with early recurrence of intrahepatic metastasis by interventional therapy is significant, which can effectively reduce the adverse reactions of patients and improve the survival rate of patients, which deserves promotion.