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解旋酶是一类能解开核苷酸双链的酶,它广泛存在于从病毒到人类等多种生物体中。自1976年人类在大肠杆菌(Esherichia Coli E.coli)中发现了第一个解旋酶,至今已有上百种解旋酶被发现,而且这一酶家族成员还在不断扩大。经过多年的研究,人们发现解旋酶具有多种功能,在细胞内它们参与DNA复制、修复、转录重组以及RNA接拼、核糖体组装、蛋白质翻译、端粒稳定。最近,还发现个别解旋酶甚至参与机
Helicases are a class of enzymes that unlock nucleotide duplexes and are found in a wide range of organisms ranging from viruses to humans. Since 1976, human beings discovered the first helicase in Escherichia Coli E. coli, so far hundreds of helicases have been discovered, and the members of this family of enzymes are still expanding. After many years of research, it has been found that helicases have multiple functions, and they are involved in DNA replication, repair, transcriptional recombination, RNA assembly, ribosome assembly, protein translation and telomere stabilization in cells. Recently, it has also been found that individual helicases even participate in the machine