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目的探讨应用人工假体置换治疗膝关节周围原发性骨肿瘤的临床效果。方法应用肿瘤型人工假体置换治疗16例膝关节周围原发恶性与侵袭性骨肿瘤切除后骨缺损,其中骨肉瘤11例,骨巨细胞瘤3例,恶性纤维组织细胞瘤2例。股骨远端10例,胫骨近端6例。结果所有患者均获随访,随访时间10～83个月,平均35.5个月。局部复发3例,假体松动1例,无假体断裂。假体3年生存率87.5%,5年生存率83.2%。术后6～12个月后MSTS功能评分为16.0～28.0分,平均24.0分。结论对膝关节周围原发恶性与侵袭性骨肿瘤切除后骨缺损采用肿瘤型人工假体重建是有效的保肢方法 。
Objective To investigate the clinical effect of artificial prosthesis replacement on primary bone tumors around knee joint. Methods Tumor - like artificial prosthesis replacement was used to treat 16 cases of primary malignant and invasive bone tumors resected around the knee. There were 11 cases of osteosarcoma, 3 cases of giant cell tumor of bone and 2 cases of malignant fibrous histiocytoma. 10 cases of distal femur and 6 cases of proximal tibia. Results All the patients were followed up for 10 ~ 83 months with an average of 35.5 months. Local recurrence in 3 cases, loose prosthesis in 1 case, no prosthesis fracture. Prosthesis 3-year survival rate of 87.5%, 5-year survival rate of 83.2%. After 6 to 12 months MSTS function score was 16.0 to 28.0 points, an average of 24.0 points. Conclusion Tumor prosthesis reconstruction is an effective method of limb salvage for the resection of primary malignant and invasive bone tumors around the knee joint.