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目的:探讨小儿风湿热及风湿性心脏病的临床特征。方法:选取我院2010年1月到2013年12月收治的68例因风湿热引起的风湿性心脏病患者,根据症状典型程度分为对照组和观察组,回顾性分析并比较两组患儿临床资料。结果:在临床表现上,观察组患儿关节痛、心力衰竭、多发性关节炎合并心脏病的发病率分别明显低于对照组,组间差异均具有统计学意义(P<0.05);而对照组患儿的心肌炎发病率显著低于观察组(P<0.05)。在实验室指标上,观察组患儿的GAS指标显著高于对照组,Cox B指标显著低于对照组;两组患者在ASO阳性人数和ERS增快发生率方面,差异不具有显著性(P>0.05)。结论:对于风湿热及风湿性心脏病患儿临床症状不典型者,应加强鉴别诊断,重视风湿热及风湿性心脏病患儿的治疗,以改善患儿预后。
Objective: To investigate the clinical features of rheumatic fever and rheumatic heart disease in children. Methods: Sixty-eight patients with rheumatic heart disease caused by rheumatic fever were selected from January 2010 to December 2013 in our hospital. The patients were divided into control group and observation group according to the typical degree of symptoms. Retrospective analysis and comparison of two groups of children clinical information. Results: The incidences of joint pain, heart failure and multiple arthritis with heart disease in the observation group were significantly lower than those in the control group, respectively, with statistical significance (P <0.05), while in the control group The incidence of myocarditis in children in the group was significantly lower than that in the observation group (P <0.05). The GAS index in the observation group was significantly higher than that in the control group, and the Cox B index was significantly lower in the observation group than in the control group. There was no significant difference between the two groups in the incidence of ASO positive rate and ERS (P > 0.05). Conclusion: For patients with atypical clinical symptoms of rheumatic fever and rheumatic heart disease, differential diagnosis should be strengthened, and the treatment of rheumatic fever and rheumatic heart disease should be emphasized to improve the prognosis of children.