结缔组织病是一种免疫复合体病,它包括系统性红斑狼疮(SLE),系统性硬皮病(PSS),皮肌炎(DM)或多发性肌炎(PM),类风湿性关节炎及风湿热,结节性动脉周围炎。此外,也有人将白塞氏综合征,韦格氏肉芽肿,干燥综合征等归入结缔组织病的近缘疾病。1972年 Sharp氏将临床上表现有类似 SLE,PSS 及DM 各种症状混合存在,但无肾脏损害,荧光抗体检查为高滴度斑点型,对皮质类固醇激素治疗反应良好的一种病,命名为混合结缔组织病(MCTD)。由于 MCTD Connective tissue disease is an immune complex disease that includes systemic lupus erythematosus (SLE), systemic scleroderma (PSS), dermatomyositis (DM) or polymyositis (PM), rheumatoid arthritis And rheumatic fever, nodular periarteritis. In addition, some people will be Behcet’s syndrome, Wegener’s granulomatosis, Sjogren’s syndrome and other related diseases classified connective tissue disease. Sharp’s clinical manifestations in 1972 will be similar to the symptoms of SLE, PSS and DM mixed existence, but no renal damage, fluorescent antibody test for high-titer type, a good response to corticosteroid treatment of a disease, named Mixed connective tissue disease (MCTD). Due to MCTD