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目的探讨保乳手术联合化疗在早期乳腺癌患者治疗中的临床疗效及对术后并发症进行分析。方法选择我院自2010年8月至2012年8月收治的94例早期乳腺癌患者,随机将患者分为对照组和治疗组,治疗组采用保乳手术联合放化疗,对照组采用传统根治术联合放化疗,并对两组的临床疗效及术后并发症进行比较和分析。结果治疗组局部复发率为6.5%(2/31),远处转移率为9.7%(3/31),1年生存率为93.5(29/31),对照组局部复发率为6.3%(4/63),远处转移率为11.1%(7/63),1年生存率为92.1(58/63),两组临床疗效差异均无统计学意义(P>0.05);治疗组乳房美观优良率为93.5%(29/31),对照组均为差,两组间差异有统计学意义(P<0.05)。结论保乳手术联合化疗应用于早期乳腺癌治疗中,在不降低临床疗效同时,能保留乳房的形体美,从而提高患者术后生活质量及增强自信心。
Objective To investigate the clinical efficacy of breast-conserving surgery combined with chemotherapy in the treatment of patients with early-stage breast cancer and analyze the postoperative complications. Methods Ninety-four patients with early-stage breast cancer who were treated in our hospital from August 2010 to August 2012 were randomly divided into control group and treatment group. The treatment group was treated with breast-conserving surgery combined with chemoradiotherapy. The control group was treated with conventional radical mastectomy Combined with radiotherapy and chemotherapy, and the clinical efficacy and postoperative complications were compared and analyzed. Results The local recurrence rate was 6.5% (2/31) in the treatment group, the distant metastasis rate was 9.7% (3/31), the one-year survival rate was 93.5 (29/31), and the control group had a local recurrence rate of 6.3% (4 / 63). The distant metastasis rate was 11.1% (7/63) and the one-year survival rate was 92.1 (58/63). There was no significant difference in clinical efficacy between the two groups (P> 0.05) The rate was 93.5% (29/31), the control group were poor, the difference between the two groups was statistically significant (P <0.05). CONCLUSION: In the treatment of early breast cancer, breast-conserving surgery combined with chemotherapy can preserve the body appearance of the breast without reducing the clinical curative effect, thereby improving the postoperative quality of life and enhancing self-confidence of patients.