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目的:评估我院经验性抗感染治疗与药敏试验结果的相符性,为规范医院抗菌药物的使用,提高临床抗感染治疗水平提供依据。方法:本次调查随机抽取我院2012年1~12月诊断为细菌感染且微生物标本“细菌培养+药敏试验”结果阳性的200份病历,根据临床经验用药与药敏试验结果的相符性,分成相符与不相符两组,通过比较药敏试验结果与临床疗效,评估药敏试验结果准确性和临床经验治疗的水平。结果:经验性抗感染治疗与药敏试验结果相符率为58.0%,药敏试验的准确率为76.5%,治疗有效率94.5%。0~3d组进行药敏试验的药敏结果相符率61.9%,治疗有效率98%;4~7d组的相符率52.2%,治疗有效率91.3%;8~15d组的相符率43.8%,治疗有效率81.1%;15d以上组的相符率42.9%,治疗有效率78.6%。结论:本院“细菌培养+药敏试验”结果对临床抗感染治疗有一定的指导意义。
OBJECTIVE: To evaluate the consistency of empirical anti-infective therapy and susceptibility testing results in our hospital so as to provide basis for standardizing the use of antimicrobial drugs in hospital and improving the level of clinical anti-infective therapy. Methods: This survey randomly selected from January to December 2012 in our hospital diagnosed as bacterial infection and microbial specimens “bacterial culture + susceptibility test ” results of 200 cases of medical records, based on clinical experience consistent with the drug susceptibility test results Sex, divided into consistent and inconsistent two groups, by comparing the drug susceptibility test results and clinical efficacy, evaluation of drug susceptibility test results and clinical experience of the treatment level. Results: The coincidence rate of empirical anti-infective therapy and susceptibility test results was 58.0%, the accuracy rate of drug susceptibility test was 76.5%, and the effective rate of treatment was 94.5%. The drug susceptibility results of 0 ~ 3d group were 61.9%, the effective rate was 98%, the coincidence rate was 52.2% in 4 ~ 7d group, the effective rate was 91.3%, and the coincidence rate in 8 ~ 15d group was 43.8% The effective rate was 81.1%. The coincidence rate was 42.9% in 15 days and the effective rate was 78.6%. Conclusion: The results of our hospital “bacterial culture + drug susceptibility test” have some guiding significance for clinical anti-infective therapy.