肾缺血再灌注损伤(renal ischemia reperfusion injury,RIRI)临床上常见的病理过程,发生于失血或中毒性休克、肾移植、肾部分切除、肾实质切开取石等手术过程中,此类手术往往需要夹闭肾血管,暂时性阻断肾供血造成短时间的缺血,一旦缺血时间过长,肾脏很容易缺血再灌注损伤,是急性肾功能衰竭 Renal ischemia reperfusion injury (renal ischemia reperfusion injury, RIRI) common in clinical pathological process occurs in the blood or toxic shock, kidney transplantation, partial nephrectomy, renal parenchymal stone removal and other surgical procedures, such surgery often Need to close the renal blood vessels, temporary block of renal blood supply caused by a short period of ischemia, once the ischemic time is too long, the kidney is very easy to ischemia-reperfusion injury, is acute renal failure