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狼疮性肾炎(LN)是系统性红斑狼疮主要死亡原因之一,也是治疗难点所在。本文报道采用每月一次静滴大剂量环磷酰胺(IVCTX)冲击治疗20例对激素治疗无效的难治性狼疮性肾炎的结果。病人和方法一、病人选择 20例LN患者均为本院门诊或住院病人,冲击前24小时尿蛋白大于3克;对强的
Lupus nephritis (LN) is one of the major causes of death of systemic lupus erythematosus, which is also the treatment of difficulties. This article reports the results of a monthly bolus injection of high dose cyclophosphamide (IVCTX) in the treatment of refractory lupus nephritis in 20 cases of hormone therapy ineffective. Patients and methods A patient selected 20 cases of LN patients were hospital outpatient or inpatient, 24 hours before the impact of urinary protein greater than 3 grams; the strong