论文部分内容阅读
氟哌酸(Norfloxacin)是喹诺酮(Quinolone)类抗菌药,结构与萘啶酸相近,亦与抗菌药吡哌酸(Pepemidic acid)相似。抗菌谱包括G-菌以及一些G~+球菌。由于分子中引进哌嗪,使之具有抗绿脓杆菌的活性。氟原子的引进可增加分子的电子稳定性及增强抗感染活性。
Norfloxacin is a quinolone antibacterial drug with a similar structure to nalidixic acid and similar antibacterial drug pepemidic acid. Antibacterial spectrum includes G-bacteria as well as some G ~ + cocci. Due to the introduction of piperazine in the molecule, it has anti-Pseudomonas aeruginosa activity. The introduction of fluorine atoms can increase the molecular electronic stability and enhance anti-infective activity.