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对20例单纯性蛋白尿的临床和病理资料进行分析。结果发现,肾功能性蛋白尿9例(45%),其中直立性蛋白尿(OP)、胡桃夹现象(NCP)各3例,OP并NCP3例;肾实质性蛋白尿11例(55%),其中肾小球性蛋白尿9例〔系膜增生性肾炎(MsPGN)3例,IgA肾病(IgAN)1例,特发性膜性肾病(IMN)2例,局灶性节段性肾小球硬化(FSGN)、轻微病变(ML)、Alport综合征(AS)各1例〕,肾小管性蛋白尿2例。对两类蛋白尿的临床特征及鉴别要点和病因进行了讨论,建议应先初筛有无OP和NCP,然后再酌情进行肾活检。
The clinical and pathological data of 20 simple proteinuria were analyzed. The results showed that renal function proteinuria in 9 cases (45%), of which 3 cases of orthostatic proteinuria (OP), nutcracker (NCP) in each case, OP and NCP in 3 cases; renal parenchymal proteinuria in 11 cases (55% Among them, 9 cases of glomerular proteinuria (mesangial proliferative glomerulonephritis (MsPGN) in 3 cases, IgA nephropathy (IgAN) in 1 case, idiopathic membranous nephropathy (IMN) in 2 cases, focal segmental renal 1 case of FSGN, 1 case of Alport syndrome, 2 cases of renal tubular proteinuria. The clinical features of two types of proteinuria and the main points of identification and etiology were discussed. It is suggested that whether OP and NCP should be preliminarily screened and renal biopsy should be conducted as appropriate.