本文报告1975年12月～1986年12月经病理证实为原发性肝癌486例的ALP、γGT检测结果。ALP、γGT的阳性率分别为72.0％和76.5％。AFP≤50ng/ml的肝癌其ALP、γGT阳性率分别为76.9％和87.7％。ALP、γGT的阳性率与疾病的早晚、肿瘤的大小、预后和生存率有密切相关。ALP、γGT均正常者其手术切除率和术后生存率显著高于升高者。因此,ALP、γGT的检测可作为肝癌诊断的辅助指标。而且有助于判断手术切除率及其预后。 This article reports 486 cases of primary liver cancer confirmed by pathology from December 1975 to December 1986 with ALP and γGT results. The positive rates of ALP and γGT were 72.0% and 76.5%, respectively. The positive rates of ALP and γGT in liver cancer with AFP ≤ 50 ng/ml were 76.9% and 87.7%, respectively. The positive rates of ALP and γGT are closely related to the disease’s sooner or later, tumor size, prognosis, and survival rate. The normal resection rate and postoperative survival rate of ALP and γGT were significantly higher than those with elevated ALP and γGT. Therefore, the detection of ALP and γGT can be used as an auxiliary index for the diagnosis of liver cancer. It also helps to determine the surgical resection rate and its prognosis.